The answer is no. Prolozone™ uses oxygen in the form of ozone to create healing. Prolotherapy uses inflammation to create healing. Prolotherapy has the following limitations: it is extremely painful, the pain usually persists for days to weeks after a treatment, it requires many injections and it is not usually effective in regenerating the cartilage in damaged knees and hips. Patients receiving Prolozone™ Therapy benefit as follows: there is minimal pain and immediate improvement, there are only a few injections, which means the treatment program is shorter and much less expensive, and it is especially effective in regenerating the cartilage in damaged knees and hips.